You should not use Jintropin if you have cancer, diabetic retinopathy, or if you are being treated for Prader-Willi syndrome and you are overweight or have severe breathing problems.

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Cynomolgus monkeys received subcutaneous injections of 1 mg/kg/week Jintrolong® or excipient control once weekly for 26 consecutive weeks, followed by a 26-week recovery period to investigate the possible vacuolation of the CP and the potential for reversibility following recovery rein non-human primates treated with Jintrolong®.

A one-compartment model with parallel zero-order and first-order absorption and first-order elimination from the central compartment welches developed to describe the PK of PEG-rhGH in pediatric patients after SC administration.

θi; is the parameter of the ith individual, θTV is the typical value of the Fortpflanzungsgemeinschaft, and ηi is the random unbekannte that stands for inter-individual variability and follows the häufig distribution with the variance of ω2.

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A functional observational battery (FOB) of neurobehavioral assessments was conducted to detect any neurobehavioral deficits resulting from potential CP dysfunction, including home cage observations, out-of-cage observations, and open field activity assessments in animals of both control and animals treated with 0.

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For preclinical studies in cynomolgus monkeys, all statistical tests were conducted as two-sided tests, and the level of significance welches Serie at 0.05. Group means and standard deviations were calculated hinein the control group and test article-treated groups. Data for each sex within a Serie were analyzed separately. The data were analyzed with the following procedures: a Levene’s test was performed to test for variance homogeneity. A one-way analysis of variance (ANOVA) was performed when the variances were not significantly different (p >0.